A simplified HPLC method for thiamine and its phosphate esters in whole blood
نویسندگان
چکیده
Thiamine, like several other B-vitamins, is essential for normal development, growth, reproduction, lactation, physical performance, and well being. It is involved in releasing energy from the macronutrients that provide energy, especially from carbohydrates. Nadel and Burger reported that patients fed intravenously for long periods were at risk for thiamine deficiency. When large amounts of glucose were administered intravenously for a prolonged period of time and without added thiamine, the concentration of Journal of Analytical Bio-Science Vol. 24, No 3 (2001)
منابع مشابه
Rapid HPLC measurement of thiamine and its phosphate esters in whole blood.
BACKGROUND Thiamine (vitamin B(1)) deficiency is associated with severe diseases such as beriberi and Wernicke encephalopathy. Although most Americans have sufficient dietary intake, thiamine deficiency is observed in the alcohol-dependent and elderly populations. Measurement of thiamine concentration in whole blood provides an assessment of vitamin B(1) status in at-risk individuals. METHOD ...
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